Phone: 610-896-4205
Office: KINSC S311


My lab is interested in understanding the mechanism of large-scale protein polymerization. Protein misfolding can lead to polymerization and we are focused on studies of how proteins involved in neurodegenerative diseases can aggregate. We are currently studying this aggregation in Huntingon's disease, Parkinson's disease, and ALS, using both worms and flies as our model systems. For an overview of this work, please see our Scientia article.

We are also interested in applying protein design to create polymers for use in biomaterials for applications in nanotechnology.

Our lab is also primarily responsible for managing the Beckman ProteomeLab XL-A Analytical Ultracentrifuge in the KINSC Instrument Core Facility.

Summer 2017

Members of the Lab:

    • Shayan Hashemi ('19)
    • Sarah Curtis ('20)
    • Jillian Wu ('20)
    • Karl Vosatka ('18)
    • Alex Belfi ('18)
    • Bashkim Kokona (research associate)
    • Catheline Phan ('18)